Wednesday, May 20, 2009

Ribavirin - Hope for Leukemia Patients at Last

ANTIVIRAL DRUG BECOMES PROMISING CANCER FIGHTER
A commonly used antiviral drug that is already used to fight hepatitis C and HIV could also be used to treat thirty percent of cancer types, according to a new study conducted on patients in Canada.
Doctors in Montreal tested the antiviral drug Ribavirin on 11 patients with acute myeloid leukemia (AML), who had undergone several other types of treatment which had failed. Nine of the patients saw their conditions improve within a matter of months, with one achieving complete remission and two achieving partial remission.
Frank Klamph, was weak and ill with AML only two months ago. After taking part in the study to test the experimental treatment, he achieved complete remission and left hospital to go scuba diving in Florida.
The researchers, led by Dr. Katherine Borden,at the Institute For Research in Immunology and Cancer (IRIC) of the Universite de Montreal, say that Ribavirin works by suppressing activity of the eIF4E gene, which becomes overactive in 30% of cancer types and over produces a protein that turns cells cancerous.
"We had remissions in several of our test patients...which is completely unheard of with their type of cancer. And,in another subgroup of patients, we had dramatic drops in the number of leukemia cells, including patients where we could no longer or barely detect any leukemia cells in their blood." Dr Borden admitted she is excited at the possibilities.
Dr Brian Leber, also involved in the study,says the results are exciting because Ribavirin is already an established drug. It has been available for a decade.So unlike other promising, untried cancer therapies that are in early stages of development,this is a drug we could use right away."These are remarkable results for people with very advanced leukemia. It is a convenient oral treatment that is well tolerated and can be taken at home. That is an exciting development."
Dr Borden says the next challenge is to combine the drug with chemotherapy to improve it's effectiveness even more and work on ways to combat possible development of resistance to the drug.
On behalf of cancer patients and their families everywhere,'WELL DONE' and thankyou.

70 comments:

  1. Katherine3:11:00 PM

    Thank heavens they are making progress on these serious illnesses. They take lives much too soon, before the person even has had time to make their histories on this planet.

    Cheers

    Hope you gals are having a lovely day!

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  2. Anonymous3:53:00 PM

    There is hope at last...the drug has been here all the time,it is so good we had a change in Gov't,now maybe everyone can see what a f^^k-up Mr. B. was..there is a couple of kids in my family that has leukemia..I have called all my family/friends to spread the good news...
    Jeannie you are a genius to find and bring this to people's attention...job well done swettie.

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  3. Anonymous4:01:00 PM

    It's as hot here as a hat-band on a dangle..hope it hold at least til they pour the concrete slab and put up the frame..how's everyone doing? You still trying to catch Nana with the flowers..haha..I know Brian is ready to go..It's this weekend right?
    Hi Katherine...hope your day is going well...
    Beautiful lady on the side-bar as always.(GIGGLES)

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  4. It's hot as blazes up here. I love it.All the flowers are perky.Brian is perky.Nana's grumpy and all is well.
    My kidney infection seems to be healing and hopefully I'll be fine for our holidays.What could be better.?Karen came over last night.She and I usually have a little cry about J.We're so happy to see her well.
    Karen seems happy.She bought a car off Brian last night.We'll probably never see the money but I don't care.She's not too good at paying her bills.Josh came over when he got out of work.He's Karen's son.He ended up borrowing the truck because the car we gave him broke down...HA!.We won't see that for a while.He better bring it back by Saturday.You need a big truck to haul our boat.
    Josh is a very nice guy,very gentle.I would trust him with anything.They are all like that in our family.Sorry for bragging about my family, but I'm proud of them.

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  5. Katherine8:40:00 PM

    Hey gals!

    Warm and breezy here in Southern CA...your families sound great, so brag about them all you want! I love the stories you are so willing to share...:)

    Cheers

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  6. Apparently the drug can treat other types of cancer too.It's a wonderful breakthrough.Another step towards beating cancer...Yay!

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  7. Anonymous9:17:00 PM

    I am so happy to hear all is well,the truck will be back in time...it's o.k.to shed a tear about J..I know how happy you both are...
    I am being selfish again..I was going to post..but I wanted every to see it today..I have got a lot of calls...I will put up tomorrow..

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  8. Anonymous9:21:00 PM

    (GIGGLES) YOU think Josh was doing a lot of poking in the back seat and broke the springs..see the hot weather has got to me..haha

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  9. Anonymous9:25:00 PM

    Hi Katherine..most of Jeannie family is genius/writers/etc.haha mine is just a horny bunch..hahaha

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  10. Anonymous9:31:00 PM

    Hell girl brag all you want..you and the ever-ready man started it all,so it feels good to be proud..Nana is in good form..we know she is feeling o.k. haha

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  11. Hi Nee!...You are in good form to night.I'm glad to hear construction is moving forward.

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  12. Mr Obama is passing a law about car emissions.I have to do some research to find out more about it.It may be significant to global warming.We need to know about it.

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  13. Anonymous10:01:00 PM

    Yep..doing good..

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  14. Anonymous10:03:00 PM

    You are helping to make people aware of what's going on ..I have learned a lot from you..thanks..

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  15. Do you and Sis share the cooking chores?How are the kids settling in to their new home?

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  16. Anonymous10:07:00 PM

    i know a lot of things like Global Warming/stem cell research I didn't think about..Obama is making an effort in trying to get a handle on the problems...

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  17. Anonymous10:10:00 PM

    They are loving it,a lot of kids to play with ..I cook when I am here ..But I always cook dinner..

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  18. Since we are running a blog open to the publiic we have some responsibility to make sure the information we put out is accurate and to some degree informative.People believe what they read, so we should respect that.

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  19. Are you all moved out of your house?

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  20. Anonymous10:15:00 PM

    This is a large house 6 bedrooms.Nan/hubby/Sharon..she is Nan's daughter...Nan has 3 kids..2 live in their old house..Sharon is 6,you know Jill is happy..they share a room.

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  21. Anonymous10:17:00 PM

    I will be finish Friday,just some furniture,no biggie...

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  22. Anonymous10:20:00 PM

    Well I was going to see if I had any gray on the choochie,I guess I will have to let my man count them(GIGGLES) I am hot tonight.hahaha

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  23. I'll bet you are glad to be done with that house.

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  24. Are you looking at any cabinets,or floors yet?

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  25. Choochies do turn grey.I haven't noticed a change yet but we don't turn grey early in our family.Nana's hair is still mostly brown.

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  26. Anonymous10:28:00 PM

    If it was left to Sis we would never move...daddy made sure all rooms was private..Sis says it seems like old times...

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  27. Sis must miss having a full house.The patter of little feet,laughter.I miss it sometimes, then I see Brian saunter by naked and I have to laugh.The freedom and privacy is wonderful.

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  28. Anonymous10:35:00 PM

    I am so glad..I have looked at a few...yes I am glad to be out..I feel so much better...the house is beautiful,it just wasn't for me..if I wanted to have neighbors on top of me ..we could still be in the apartment...

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  29. Anonymous10:36:00 PM

    For the price they ,it's a small lot..I guess they charge for the water front.

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  30. Oh yeah,waterfront property is always expensive.Well now you have a couple of acres to run around on.You could build a barn for the kids' ponies and still have lots of room.And at least you like the neighbors you will have there.

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  31. Anonymous10:43:00 PM

    I just asked Gil will he look and see ...the fool said come there he will let little gil see,funny..Yes Sis do miss having a full hose to boss around,there was 7 of us here..her three kids ..daddy/Chris/me.

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  32. Anonymous10:49:00 PM

    Jeannie's ...these two crazy men of mine is talking about pigs/cows/horses/cows/chickens/ the works...I told them no way...Dad say when you want a steak,just go kill a cow..I swear that man has change a lot since he met us.

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  33. How old is Gil 56? he sure is horny for an old guy.You must know how to push the right buttons.

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  34. Yeah,before they met you they didn't know steaks came from cows,they thought they came from packages.

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  35. Those guys would step in one cow pie and give up farming.

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  36. Anonymous11:00:00 PM

    Nan called a lot of people to tell them to read the post,I wanted it to be the first thing they see..Nan says she is our PR person.

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  37. Are you really going to have chickens? What fun.Jill can name them.If she is a tomboy she will love animals.I sure did.

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  38. Anonymous11:07:00 PM

    Gil is 55 last April...yes he is a horny old fart..hahaha...Dad is 79/78 ..dad says a man should settle for one woman and he will last a long time..

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  39. Anonymous11:12:00 PM

    Yes we will have a few chickens,that it...maybe a couple of ponies ,we will have to see..thats it..Sis say dad wouldn't know which cow to milk,he might try to milk the bull if you tell him she had only one tit.haha

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  40. I'd like to see him milk that bull.
    You can cure them both of being amateur farmers by asking them to shovel the chicken shit out of the coop.

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  41. Anonymous11:18:00 PM

    That is so great Karen got the car,she is a warm and loving person...I know for a fact she can have anything you have...Josh will have the car back for the weekend.

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  42. Josh is a bit of a dark horse,a mystery man,but a very sweet guy.
    I will always give anything I have to Karen.I can never repay her and you know why.

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  43. Anonymous11:23:00 PM

    I don't have to worry..dad/Gil is not going farm...both say they was going to work in my garden...

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  44. Anonymous11:28:00 PM

    Yep I know...sweetie you and the ever-ready man was meant for each other...we both was in love with love..since we found true love ..ain't love grand..great hubby's and great poking.hahaha...you know we have great kids and family.

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  45. That would be a nice healthy activity for them.There's nothing like making things grow and harvesting your own food.It gives you a good feeling.

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  46. Anonymous11:35:00 PM

    My brothers said that Gil was the best for me,ha e has been around the block a couple of times and never married...he had no baggage and was older...they did a back-ground check on my man...Jon says he didn't want me to get another Ron...hahaha

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  47. Isn't it great that they protected you like that?

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  48. Anonymous11:43:00 PM

    You remember dad's driver..that's who brought the house..Leon is aunt Mae's son,dad's sister.His wife loves it..but she is from Reno,kind of dizzy..hahaha

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  49. Anonymous11:46:00 PM

    AWwww shit,they say when I was born the doctor dropped me on my fool head..
    They have always been that way,I guess all was groung except Chris when I was born...

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  50. My family didn't like Brian at first because he was divorced and had kids.They thought I was taking on more problems.

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  51. Anonymous11:48:00 PM

    Everyone thought I was sis kid when daddy moved us here.

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  52. Anonymous11:53:00 PM

    You proved them wrong...your dad liked Brian and I think the Major had good feeling about him...a lot of times you can married the wrong people...but it's nice to know we both got it right the second time..

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  53. Well the gators in that lake can bite her ass.You won't be there.

    I would be too nervous to fish or swim there anyway.I like being here where you can swim anywhere in safety.

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  54. Brian is okay.Nana still doesn't like him,but you're right,dad liked him.

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  55. Anonymous12:01:00 AM

    I just asked dad now old he was ..he is 81 years old..

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  56. Anonymous12:06:00 AM

    Nana only liked your dad..she is o.k. I guess..she is about material things..she will be fine up there..the gators is mostly in the swamp area...I just didn't like it there...it never felt like mine.

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  57. Anonymous12:09:00 AM

    We have a beach...to be safe ,i think we will get a pool...I have never seen a snake here...

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  58. Have you ever noticed houses have a friendly feel to them or a hostile feel or a cold souless feel.They can speak to you if you listen.

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  59. According to that psychic Cynthia Brown on Montel,it's not always the house that gives off vibes ,it's often the land it stands on and what happened there at some time in the past.

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  60. I've kept you up too late .I'm sorry.I love talking to you.We have a real connection.If you want to say goodnight,that's okay.

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  61. Anonymous12:29:00 AM

    I love talking to you also...I think the psychic was right..so much happen to me there.

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  62. Anonymous12:33:00 AM

    The Limo broke down on the way to Reno...had to return home and let dad and Gil go on to Reno...my legs was worked on...my lights went out,had to go to the hotel..my appendix was removed..

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  63. I have walked into some houses that have frightened me. They have such an evil feeling.AS a little girl I was more sensitive to it

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  64. Don't forget your eye surgery.

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  65. Anonymous12:38:00 AM

    I will put up a post tomorrow and also the recipe for you to take to the lake...quick and easy..eat what you catch..it's not Tacos,it's Fajitas..our kids love them ...very filling...

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  66. A fish fajita????interesting.

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  67. Well,I guess we should say good night and I hope you have no more health emergencies.Have a good one Sweetie.Your friend ...J

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  68. Anonymous12:44:00 AM

    Yes my eye surgery and all that in less than a year..Gilly was a week old when we moved...Kids are very sensitive to bad vibes...it was certain places in the yard Jill would not play...

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  69. Anonymous12:47:00 AM

    ou can use any kind of meat you like..
    Yes sweetie I will say goodnite..you still have a lot of rest to get...see you tomorrow...Sweet dreams from me to you...LUV...LUV...NEE

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  70. PS..Kids are sensitive to the atmosphere of a place.Ms. Brown says that children can see spirits and angels and they talk to them.Jill could feel something.

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